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Celtics vs. Nuggets predictions: Odds, recent stats, trends and best bets for February 25

The Boston Celtics (38-19) wrap up a four-game road trip tonight at Ball Arena against the Denver Nuggets (36-22) in a battle of NBA heavyweights.

The Celtics have won each of the first three games on this West Coast road trip and four games in a row overall while the Nuggets have alternated wins and losses over their last six games.

Denver’s lack of consistency is in large part due to the absence of the injured Aaron Gordon (hamstring). Sunday night they lost in San Francisco to the Warriors, 128-117. The loss came in spite of another triple double from Nikola Jokic (35 points, 20 rebounds, 12 assists).

Boston takes the court tonight after winning last night in Phoenix, 97-81. Jaylen Brown (knee) was out injured but Derrick White scored 22 and Sam Hauser was 4-10 from deepto pace the attack against a Suns’ team minus their starting backcourt of Dillon Brooks and Devin Booker.

With Brown’s availability in question for the Celtics, Denver’s ability to defend the perimeter will be that much more critical. No doubt they will rely on their efficiency from inside the arc and their rebounding in an attempt to counter Boston's 3-point heavy approach.

Lets take a closer look at the matchup and take into consideration lineups, injuries, and other factors affecting the line and total.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds courtesy of DraftKings recent team performance, player stats, and of course, our predictions, picks best bets for the game from our modeling tools and staff of experts.

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Game Details and How to Watch Live: Celtics at Nuggets

  • Date: Wednesday, February 25, 2026
  • Time: 10PM EST
  • Site: Ball Arena
  • City: Denver, CO
  • Network/Streaming: ESPN

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Game Odds: Celtics at Nuggets

The latest odds as of Wednesday courtesy of DraftKings:

  • Moneyline: Boston Celtics (+136), Denver Nuggets (-162)
  • Spread: Nuggets -3.5
  • Total: 228.5 points

This game opened Nuggets -3.5 with the Total set at 228.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NBA schedule! 

Expected Starting Lineups: Celtics at Nuggets

Boston Celtics

  • PG Derrick White
  • SG Ron Harper Jr.
  • SF Baylor Scheierman
  • PF Sam Hauser
  • C Neemias Queta

Denver Nuggets

  • PG Jamal Murray
  • SG Julian Strawther
  • SF Christian Braun
  • PF Cam Johnson
  • C Nikola Jokic

Injury Report: Celtics at Nuggets

Boston Celtics

  • Jaylen Brown (knee)is listed as questionable for tonight’s game
  • Jason Tatum (Achilles) has been declared OUT of tonight’s game

Denver Nuggets

  • Jamal Murray (hamstring) is listed as probable for tonight’s game
  • Julian Strawther (toe) is listed as probable for tonight’s game
  • Aaron Gordon (hamstring) has been declared OUT of tonight’s game
  • Jalen Pickett (knee) has been declared OUT of tonight’s game
  • Peyton Watson (hamstring) has been declared OUT of tonight’s game
  • Tamar Bates (foot) has been declared OUT of tonight’s game

Important stats, trends and insights: Celtics at Nuggets

  • The Nuggets are 15-11 at home this season
  • The Celtics are 20-10 on the road this season
  • The Nuggets are 32-26 ATS this season / 12-14 at home
  • The Celtics are 33-23-1 ATS this season / 20-9-1 on the road
  • The OVER has cashed in just 21 of the Celtics’ 57 games this season (21-36)
  • The OVER has cashed in 37 of the Nuggets’ 58 games this season (37-21)
  • The Celtics are 8-2 ATS in their last 10 games
  • The Game Total UNDER has cashed the last 3 times these teams have played
  • The Celtics are 14-6 this season against the Western Conference
  • Nikola Jokic is AVERAGING 28.8 points, 12.5 rebounds, and 10.5 assists per game this season

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NBA calendar based on data points like recent performance, head-to-head player matchups, trends information and projected game totals.
 
Once the model is finished running, we put its projections next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for tonight’s Celtics and Nuggets’ game:

  • Moneyline: Rotoworld Bet is leaning towards a play on the Nuggets on the Moneyline
  • Spread: Rotoworld Bet is recommending a play on the Nuggets -3.5 ATS
  • Total: Rotoworld Bet is leaning towards a play on the Game Total OVER 228.5

Want even more NBA best bets and predictions from our expert staff & tools? Check out the Expert NBA Predictions page from NBC Sports for money line, spread and over/under picks for every game on today’s calendar! 

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our NBA Top Trends tool on NBC Sports!

Follow our experts on socials to keep up with all the latest content from the staff: 

  • Jay Croucher (@croucherJD)
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  • Vaughn Dalzell (@VmoneySports) 
  • Trysta Krick (@Trysta_Krick) 

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