Viewers in the UK can watch the match live on ITV1 starting at 4:10pm GMT, with a stream available on ITVX. The match marks a crucial Six Nations clash at Murrayfield, where Gregor Townsend's side looks to respond following a loss to Italy.
Scotland make four changes to the pack, with Nathan McBeth starting at loosehead. England, meanwhile, remains settled with captain Maro Itoje returning to the second row.